GM-CSF facilitates the development of inflammation-associated colorectal carcinoma
نویسندگان
چکیده
The granulocyte macrophage colony-stimulating factor (GM-CSF) is known to play a protective role in intestinal inflammation. However, the effects of GM-CSF on the progression of colitis to colorectal carcinoma have long remained unclear. We have recently demonstrated that GM-CSF produced by colonic epithelial cells promotes colorectal tumorigenesis by stimulating the secretion of vascular endothelial growth factor.
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Evaluation of pre-treatment serum levels of IL-7 and GM-CSF in colorectal cancer patients
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